Disease: Microcephaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZNHIT3 Q15649 zinc finger HIT-type containing 3 5.5E-07 0.666 0.462
ZIC2 O95409 Zic family member 2 Transcription factor 0.97 0.556 0.769
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
WDR81 Q562E7 WD repeat domain 81 6.7E-08 0.670 0.462
WDPCP O95876 WD repeat containing planar cell polarity effector 1.1E-10 0.576 0.769
UFD1 Q92890 ubiquitin recognition factor in ER associated degradation 1 1.00 0.537 0.769
UBE2T Q9NPD8 ubiquitin conjugating enzyme E2 T 1.1E-05 0.550 0.731
TUBB3 Q13509 tubulin beta 3 class III Cellular structure 2.6E-10 0.486 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769
TMEM231 Q9H6L2 transmembrane protein 231 3.1E-07 0.554 0.692
TMEM216 Q9P0N5 transmembrane protein 216 1.9E-03 0.544 0.615
TMEM107 Q6UX40 transmembrane protein 107 3.1E-08 0.592 0.692
TCTN2 Q96GX1 tectonic family member 2 1.8E-14 0.578 0.654
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
SUMF1 Q8NBK3 sulfatase modifying factor 1 2.3E-08 0.641 0.538
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885
SLX4 Q8IY92 SLX4 structure-specific endonuclease subunit 1.6E-22 0.565 0.731
SLC25A24 Q6NUK1 solute carrier family 25 member 24 Transporter 3.4E-12 0.575 0.731
SLC20A2 Q08357 solute carrier family 20 member 2 Transporter 0.97 0.638 0.577
SLC13A5 Q86YT5 solute carrier family 13 member 5 Transporter 5.1E-04 0.608 0.577